As we age, various factors contribute to the natural progression of the aging process. One lesser-known but significant contributor is glycation, a biochemical process that plays a crucial role in the aging of our cells and tissues. This process, fueled by excess sugar, can quietly impact our health and lifespan.
The Science of Glycation
Glycation is when sugar molecules attach to proteins and lipids, forming what we call advanced glycation end-products (AGEs). These AGEs can trigger inflammation and oxidative stress, contributing to various age-related diseases.
Glycation: Collagen & Elasticity
Collagen, a crucial protein providing structure and elasticity to our skin, tends to be a prime target for glycation. When collagen molecules are glycated, they lose their flexibility and resilience. This results in the formation of wrinkles, sagging skin, and a decrease in overall skin elasticity, all of which are characteristic signs of aging.
Impaired Cellular Function
Glycation affects the function of proteins and enzymes in our cells. This interference can lead to a decline in cellular function, impacting vital processes such as DNA repair, energy production, and cellular communication. Over time, these disruptions contribute to the overall aging of tissues and organs.
Inflammation and Oxidative Stress
The presence of AGEs triggers an inflammatory response in the body. Inflammation, combined with increased oxidative stress, accelerates the aging process. Chronic inflammation is linked to various age-related diseases, including cardiovascular disease, neurodegenerative disorders, and diabetes.
Impact on Organs and Systems
Glycation is not limited to the skin; it affects organs and systems throughout the body. For instance, glycation in blood vessels can contribute to arterial stiffness, potentially leading to hypertension and cardiovascular issues. In the eyes, glycation plays a role in the development of cataracts.
Protecting Against Glycation
To combat glycation, it's important to maintain healthy blood sugar levels. This involves making smart dietary choices, opting for whole foods over sugary treats, and increasing antioxidant intake from fruits and vegetables.
Can supplementation help?
To help combat the effects of the glycation process, we formulated Longevity with a blend of nutrients and antioxidant, such as nicotinamide riboside, liposomal glutathione and CoQ10. With regular use and in combination with being sugar conscious, it can help protect against the harmful effects of excess sugar and promote overall well-being.
Reference
Suji, George, and S. Sivakami. "Glucose, glycation and aging." Biogerontology 5 (2004): 365-373.
